Pre-Surgery Demographic, Clinical, and Symptom Characteristics Associated with Different Self-Reported Cognitive Processes in Patients with Breast Cancer
| Autor: | Yu-Yin Allemann-Su, Marcus Vetter, Helen Koechlin, Steven M. Paul, Bruce A. Cooper, Kate Oppegaard, Michelle Melisko, Jon D. Levine, Yvette Conley, Christine Miaskowski, Maria C. Katapodi |
|---|---|
| Přispěvatelé: | University of Zurich, Katapodi, Maria C |
| Rok vydání: | 2022 |
| Předmět: |
Cancer Research
10093 Institute of Psychology Depression Oncology and Carcinogenesis cancer-related cognitive impairment cognitive flexibility working memory Brain Disorders inhibitory control 10057 Klinik für Konsiliarpsychiatrie und Psychosomatik breast cancer Mental Health Good Health and Well Being Oncology Clinical Research Behavioral and Social Science 2730 Oncology 1306 Cancer Research 150 Psychology Cancer |
| Zdroj: | Cancers, vol 14, iss 13 Cancers; Volume 14; Issue 13; Pages: 3281 |
| DOI: | 10.5167/uzh-227812 |
| Popis: | Cancer related cognitive impairment (CRCI) is a common and persistent symptom in breast cancer patients. The Attentional Function Index (AFI) is a self-report measure that assesses CRCI. AFI includes three subscales, namely effective action, attentional lapses, and interpersonal effectiveness, that are based on working memory, inhibitory control, and cognitive flexibility. Previously, we identified three classes of patients with distinct CRCI profiles using the AFI total scores. The purpose of this study was to expand our previous work using latent class growth analysis (LCGA), to identify distinct cognitive profiles for each of the AFI subscales in the same sample (i.e., 397 women who were assessed seven times from prior to through to 6 months following breast cancer surgery). For each subscale, parametric and non-parametric statistics were used to determine differences in demographic, clinical, and pre-surgical psychological and physical symptoms among the subgroups. Three-, four-, and two-classes were identified for the effective action, attentional lapses, and interpersonal effectiveness subscales, respectively. Across all three subscales, lower functional status, higher levels of anxiety, depression, fatigue, and sleep disturbance, and worse decrements in energy were associated with worse cognitive performance. These and other modifiable characteristics may be potential targets for personalized interventions for CRCI. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|