Control of lower extremity edema in patients with diabetes: double blind randomized controlled trial assessing the efficacy of mild compression diabetic socks
| Autor: | Sai V. Yalla, Charles A. Andersen, Jacquelyn Ortiz, Ryan T. Crews, Stephanie C. Wu, Michelle Winder, Julia Overstreet, Melissa K Skratsky |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system Endocrinology Diabetes and Metabolism Population 030204 cardiovascular system & hematology Article law.invention Diabetes Complications 03 medical and health sciences Peripheral Arterial Disease 0302 clinical medicine Endocrinology Randomized controlled trial Double-Blind Method law Diabetes mellitus Edema Compression Bandages Internal Medicine medicine Humans Ankle Brachial Index 030212 general & internal medicine education Aged education.field_of_study business.industry Repeated measures design General Medicine Middle Aged medicine.disease Surgery medicine.anatomical_structure lcsh:RC666-701 Anesthesia Toe Brachial Index Female medicine.symptom Ankle business Body mass index |
| Zdroj: | Veins and Lymphatics, Vol 6, Iss 1 (2017) |
| ISSN: | 2279-7483 |
| DOI: | 10.4081/vl.2017.6637 |
| Popis: | Aims Persons with diabetes frequently present with lower extremity (LE) edema; however, compression therapy is generally avoided for fear of compromising arterial circulation in a population with a high prevalence of peripheral arterial disease. This double blind randomized controlled trial (RCT) assessed whether diabetic socks with mild compression could reduce LE edema in patients with diabetes without negatively impacting vascularity. Methods Eighty subjects with LE edema and diabetes were randomized to receive either mild-compression knee high diabetic socks (18–25mmHg) or non-compression knee high diabetic socks. Subjects were instructed to wear the socks during all waking hours. Follow-up visits occurred weekly for four consecutive weeks. Edema was quantified through midfoot, ankle, and calf circumferences and cutaneous fluid measurements. Vascular status was tracked via ankle brachial index (ABI), toe brachial index (TBI), and skin perfusion pressure (SPP). Results Seventy-seven subjects (39 controls and 38 mild-compression subjects) successfully completed the study. No statistical differences between the two groups in terms of age, body mass index, gender, and ethnicity. Repeated measures analysis of variance and Sidak corrections for multiple comparisons were used for data analyses. Subjects randomized to mild-compression diabetic socks demonstrated significant decreases in calf and ankle circumferences at the end of treatment as compared to baseline. LE circulation did not diminish throughout the study with no significant decreases in ABI, TBI or SPP for either group. Conclusions Results of this RCT suggest that mild compression diabetic socks may be effectively and safely used in patients with diabetes and LE edema. |
| Databáze: | OpenAIRE |
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