Stroke care trends during COVID-19 pandemic in Zanjan Province, Iran. From the CASCADE Initiative: statistical analysis plan and preliminary results
| Autor: | Saltanat Kamenova, Clio Rubinos, Matías Alet, Henry Ma, Nawaf Yassi, M. Reza Azarpazhooh, Brian Silver, Omer Iqbal, Ramin Zand, Sean Ruland, Cristian F Isaac, Jerzy Krupinski, Mario Di Napoli, Masoom Desai, Shahram Arsang-Jang, Tarun Girotra, Annemarei Ranta, Rubens José Gagliardi, Yongchai Nilanont, Reza Bavarsad Shahripour, Yama Akbari, P N Sylaja, Sandy Steinwender, Negar Morovatdar, Animesh Gupta, Simona Lattanzi, Michel T. Torbey, Abdoreza Ghoreishi, Hamidon Basri, Saverio Stranges, Aida Kondybayeva, Takeshi Yoshimoto, Manabu Inoue, Shahram Abootalebi, Hamidreza Saber, Stephan A. Mayer, Thanh N. Nguyen, Ziad Sabaa-Ayoun, James E. Siegler, Maria C Zurru, Afshin A. Divani, Elizabeth Macri, Thanh G. Phan, José Biller, Christa O'Hana S. Nobleza, Afshin Borhani-Haghighi, Diana Yorio |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Time Factors Epidemiology medicine.medical_treatment 8.1 Organisation and delivery of services Iran stroke care Brain Ischemia Brain ischemia 0302 clinical medicine Modified Rankin Scale Health care Pandemic 80 and over Thrombolytic Therapy Hospital Mortality Stroke Outcome Aged 80 and over education.field_of_study Rehabilitation Thrombolysis Middle Aged Hospitalization Outcome and Process Assessment Health Care Treatment Outcome Stroke care outcome Female epidemiology Patient Safety Cardiology and Cardiovascular Medicine Intracranial Hemorrhages Health and social care services research medicine.medical_specialty Population Clinical Sciences Clinical Neurology and over Outcome and Process Assessment Article Time-to-Treatment 03 medical and health sciences medicine Humans cardiovascular diseases Mortality education Aged Disability Neurology & Neurosurgery business.industry Neurosciences COVID-19 Bayes Theorem Interrupted Time Series Analysis Recovery of Function Length of Stay medicine.disease mortality Brain Disorders Health Care Good Health and Well Being disability Emergency medicine Surgery Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Stroke and Cerebrovascular Diseases Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, vol 29, iss 12 Epidemiology and Biostatistics Publications |
| ISSN: | 1532-8511 1052-3057 |
| Popis: | BackgroundThe emergence of the COVID-19 pandemic has significantly impacted global healthcare systems and this may affect stroke care and outcomes. This study examines the changes in stroke epidemiology and care during the COVID-19 pandemic in Zanjan Province, Iran.MethodsThis study is part of the CASCADE international initiative. From February 18, 2019, to July 18, 2020, we followed ischemic and hemorrhagic stroke hospitalization rates and outcomes in Valiasr Hospital, Zanjan, Iran. We used a Bayesian hierarchical model and an interrupted time series analysis (ITS) to identify changes in stroke hospitalization rate, baseline stroke severity [measured by the National Institutes of Health Stroke Scale (NIHSS)], disability [measured by the modified Rankin Scale (mRS)], presentation time (last seen normal to hospital presentation), thrombolytic therapy rate, median door-to-needle time, length of hospital stay, and in-hospital mortality. We compared in-hospital mortality between study periods using Cox-regression model.ResultsDuring the study period, 1,026 stroke patients were hospitalized. Stroke hospitalization rates per 100,000 population decreased from 68.09 before the pandemic to 44.50 during the pandemic, with a significant decline in both Bayesian [Beta: -1.034; Standard Error (SE): 0.22, 95% CrI: -1.48, -0.59] and ITS analysis (estimate: -1.03, SE = 0.24, p |
| Databáze: | OpenAIRE |
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