Comparison of EUS-guided versus percutaneous and transjugular approaches for the performance of liver biopsies
| Autor: | Amal Shukri, Andre Fialho, Carmen Smotherman, Andrea Fialho, Silvio W. de Melo, Ciel Harris, Ahmad Alkhasawneh, Miguel Malespin, Asim Shuja |
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| Rok vydání: | 2018 |
| Předmět: |
Endoscopic ultrasound
Image-Guided Biopsy Male medicine.medical_specialty Percutaneous Endosonography 03 medical and health sciences 0302 clinical medicine Fibrosis Biopsy medicine Humans Endoscopic Ultrasound-Guided Fine Needle Aspiration Retrospective Studies Hepatology medicine.diagnostic_test business.industry Gastroenterology Interventional radiology Middle Aged medicine.disease digestive system diseases Tissue acquisition Liver Needles 030220 oncology & carcinogenesis Liver biopsy 030211 gastroenterology & hepatology Female Radiology Specimen length business |
| Zdroj: | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 51(6) |
| ISSN: | 1878-3562 |
| Popis: | Background Liver biopsy through endoscopic ultrasound (EUS) has become a novel approach for tissue acquisition. We aim to evaluate the adequacy of EUS-guided liver biopsies in comparison to those obtained through interventional radiology (IR) techniques. Methods A retrospective single-center analysis was performed of all IR (transjugular or image-guided percutaneous) and EUS-guided liver biopsies performed at an academic medical center from January 2016 to January 2018. Patient demographics, histologic characteristics, and clinical outcomes were collected. Results 152 procedures were included for analysis. 45% of liver biopsies were performed through EUS-guidance. The most common indication for liver biopsy was NASH fibrosis staging (n = 64). IR-guided biopsies contained a higher number of complete portal triads (13.6 vs. 10.8 p ≤ 0.01) while EUS-guided biopsies produced an increased total specimen length (4.6 cm vs. 3.6 cm p ≤ 0.01).47% of biopsy samples were fragmented with the majority of these (72%) occurring with EUS-guided procedures (p ≤ 0.01). IR-guided biopsies led to more complications in comparison to EUS-guided procedures (p = 0.03) Conclusion Liver biopsies performed through EUS-guidance are comparable to IR-guided liver biopsies and may have an enhanced safety profile with acceptable tissue acquisition characteristics. Standardization of techniques and needles is needed for optimization of tissue sampling. |
| Databáze: | OpenAIRE |
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