Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats
| Autor: | Charles W. Hewitt, Steven W. Marra, R D O Chad Gordon, Steven M. Hollenberg, Louise F. Strande, Martha S. Matthews, Massimiliano Guglielmi, Daniel R. Lefebvre, Jad Skaf |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Transplantation Heterotopic Carotid Artery Common medicine.medical_treatment Pulmonary Artery Doppler echocardiography Heart Rate Internal medicine medicine Animals Echocardiography Doppler Pulsed Heart transplantation Heart transplants Graft rejection medicine.diagnostic_test business.industry Anastomosis Surgical Microsurgery Rats Rats Inbred ACI Surgery Femoral Artery Rats Inbred Lew Cardiology Heart Transplantation business |
| Zdroj: | Microsurgery. 27:240-244 |
| ISSN: | 1098-2752 0738-1085 |
| Popis: | Noninvasive assessment of heterotopic heart transplants using Doppler echocardiography was first described in two patients by Allen at Stanford in 1981. Since then, numerous experiments studying heterotopic heart transplantation in humans and large animals have confirmed its utility by employing either an intra-abdominal or cervical model. In rats, however, prior research investigating intra-abdominal heterotopic hearts has showed echocardiography to be ineffective. We have recently developed a new technique for heterotopic femoral heart transplantation in rats, which employs the novel use of trans-femoral echocardiography. Therefore, our goal was to re-examine the efficacy of echocardiography for detection of graft rejection. © 2007 Wiley-Liss, Inc. Microsurgery, 2007. |
| Databáze: | OpenAIRE |
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