Vitamin A deficiency among under-five Nigerian children with diarrhoea
| Autor: | Olufunmilola O Abolurin, Adebanjo J. Adegbola, Oyeku A Oyelami, Samuel Ademola Adegoke, Oluseye O. Bolaji |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Vitamin
Diarrhea Male Pediatrics medicine.medical_specialty 030231 tropical medicine Serum retinol Nigeria Nigerian children Severity of Illness Index 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Risk Factors Vitamin A deficiency medicine Humans Vitamin A Wasting Under-five business.industry Wasting Syndrome Vitamin A deficiency Nigerian children diarrhoea Infant General Medicine Articles medicine.disease diarrhoea Increased risk Cross-Sectional Studies chemistry Child Preschool 030221 ophthalmology & optometry Female medicine.symptom business |
| Zdroj: | African Health Sciences African Health Sciences; Vol 18, No 3 (2018); 737-742 |
| ISSN: | 1729-0503 1680-6905 |
| Popis: | Background: Vitamin A deficiency (VAD) and diarrhoea are still important contributors to childhood deaths in Africa, and vitamin A deficient children are at increased risk as well as severity of diarrhoea. Objectives: To determine the prevalence of VAD and identify the associated factors among children with diarrhoea. Methods: The study was a hospital-based cross-sectional descriptive study. Consecutive children with diarrhoea were recruited, provided they met the inclusion criteria. Serum retinol levels were determined by high performance liquid chromatography (HPLC) in one hundred and seventy under-five children who presented with diarrhoea at the Wesley Guild Hospital, Ilesa, Nigeria. Results: The serum retinol levels of the children ranged from 0.29 – 2.35 µmol/L with a mean ± SD of 1.07 ± 0.42 µmol/L. Twenty seven (15.9%) were vitamin A deficient with three (1.8%) of these having severe VAD. Wasting was significantly associated with a higher prevalence of VAD [p = 0.023, OR (95% CI) = 3.08 (1.21 - 7.79)]. A significantly greater proportion of the subjects who had VAD were hospitalized, compared with the non-deficient ones [p = 0.001, OR (95% CI) = 4.40 (1.82 - 10.66)]. The only subject who died was vitamin A deficient. Conclusion: Wasting and hospitalization are factors that may indicate the presence of VAD in a child with diarrhoea. Vitamin A supplements should therefore be given, as part of the treatment for diarrhoea, to children who have wasting, especially when they require hospitalization. Keywords: Vitamin A deficiency, Nigerian children, diarrhoea. |
| Databáze: | OpenAIRE |
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