Ultrasound/radiation-responsive emulsions
| Autor: | Gaio Paradossi, Gabriela Calderó |
|---|---|
| Přispěvatelé: | European Commission, Ministerio de Ciencia, Innovación y Universidades (España) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Polymers and Plastics Microfluidics Nanotechnology 02 engineering and technology emulsion nanodroplets microbubbles ultrsounds acoustic droplets vaporization optical droplets vaporization drug delivery imaging micro-machines radiation dosimetry 010402 general chemistry 01 natural sciences Acoustic droplets vaporization Imaging Ultrasounds Colloid and Surface Chemistry Settore CHIM/02 Radiation dosimetry Physical and Theoretical Chemistry Nanodroplets Ultrasound irradiation Preparation procedures Microbubbles Emulsion Sonodynamic therapy Surfaces and Interfaces 021001 nanoscience & nanotechnology 0104 chemical sciences Drug delivery Micro-machines 0210 nano-technology Optical droplets vaporization Ultrasound Radiation |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | The design of emulsions containing systems able to respond to different kinds of perturbations is attracting increasing interest for biomedical purposes. Emulsions of phase-change droplets, which undergo a liquid-to-gas transition on ultrasound or radiation activation are the most representative examples of such emulsions. Activation should be achieved within clinically acceptable settings, demanding a careful design of such emulsions, encompassing the selection of the components as well as the preparation procedures. New developments making use of microfluidics or low-energy emulsification methods are emerging to ensure the production of droplets of controlled size and minimal polydispersity. Furthermore, investigations on the properties of the droplets shell offer new insight for the understanding of their stability and acoustic behaviour under ultrasound irradiation. Emulsion-mediated sonodynamic therapy and the ground-breaking research on the ultrasound-propelled motors are also discussed in this review, in the light of the most recent literature. This work was partially supported by EU H2020 ‘AMPHORA’, contract n. 766456. Financial support from the Spanish Ministry of Science, Innovation and Universities (CTQ2017-84998-P project), Agencia Estatal de Investigación (AEI), the European Regional Development Fund (Fondo Europeo de Desarrollo Regional, FEDER), and Generalitat de Catalunya (2017SGR1778 Consolidated Group Grant) is acknowledged. The collaboration of the Grupo de Nanotecnología Farmacéutica, of the University of Barcelona (UB), headed by MJ Garcia-Celma in the Faculty of Pharmacy and Food Sciences, which forms an R&D Associated Unit to CSIC, is also acknowledged. GC is currently a Serra Húnter Fellow at the Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry of the Faculty of Pharmacy and Food Sciences of the University of Barcelona, Spain. |
| Databáze: | OpenAIRE |
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