Enteric pathogens associated with childhood diarrhea in Tripoli-Libya
| Autor: | Ezzedin Franka, Hind I. Shaheen, Omar Abusnena, John D. Klena, Abdalwahed A. Abobker, Khalifa Sifaw Ghenghesh, Zaineb Krema, Amal Rahouma, Hanan El Mohammady, Khalid Treesh, Abdulhafid Abudher |
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| Rok vydání: | 2011 |
| Předmět: |
Diarrhea
Male Rotavirus Salmonella Population Drug resistance Libya Biology medicine.disease_cause Microbiology Feces Anti-Infective Agents Ciprofloxacin Virology Drug Resistance Bacterial medicine Escherichia coli Prevalence Humans education education.field_of_study Norovirus Infant Newborn Infant Articles biology.organism_classification Infectious Diseases Aeromonas Child Preschool Parasitology Female medicine.symptom medicine.drug |
| Zdroj: | The American journal of tropical medicine and hygiene. 84(6) |
| ISSN: | 1476-1645 |
| Popis: | Stool samples from children < 5 years of age with diarrhea (N = 239) were examined for enteric pathogens using a combination of culture, enzyme-immunoassay, and polymerase chain reaction methods. Pathogens were detected in 122 (51%) stool samples; single pathogens were detected in 37.2% and co-pathogens in 13.8% of samples. Norovirus, rotavirus, and diarrheagenic Escherichia coli (DEC) were the most frequently detected pathogens (15.5%, 13.4%, and 11.2%, respectively); Salmonella, adenovirus, and Aeromonas were detected less frequently (7.9%, 7.1%, and 4.2%). The most commonly detected DEC was enteroaggregative E. coli (5.4%). Resistance to ≥ 3 antimicrobials was observed in 60% (18/30) of the bacterial pathogens. Salmonella resistance to ciprofloxacin (63.1%) has become a concern. Enteric viral pathogens were the most significant causative agents of childhood diarrhea in Tripoli. Bacterial pathogens were also important contributors to pediatric diarrhea. The emergence of ciprofloxacin-resistant Salmonella represents a serious health problem that must be addressed by Libyan health authorities. |
| Databáze: | OpenAIRE |
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