Neutralizing antibody assay for human Herpesvirus-6
| Autor: | Takehiko Yazaki, Yoshizo Asano, Takao Ozaki, Sadao Suga, Tetsushi Yoshikawa |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
biology
viruses Dose-Response Relationship Immunologic Fluorescent Antibody Technique Exanthema Subitum Antibodies Viral Fetal Blood biology.organism_classification Peripheral blood mononuclear cell Virology Virus Neutralization Culture Media Infectious Diseases Neutralization Tests Cord blood Tumor Cells Cultured biology.protein Humans Human herpesvirus 6 Antibody Neutralizing antibody Herpesviridae |
| Zdroj: | Journal of Medical Virology. 30:14-19 |
| ISSN: | 1096-9071 0146-6615 |
| DOI: | 10.1002/jmv.1890300104 |
| Popis: | Antibody to human herpesvirus-6 (HHV-6) was measured in cord blood mononuclear cell cultures by a neutralization (NT) test, in which the presence or absence of characteristic large cell formation in cells infected with HHV-6 was used as an indicator for neutralization of the virus. The NT test could measure antibodies during and just after the appearance of the skin rash in patients with exanthem subitum. The levels of antibodies measured by the NT test was generally higher than that by an indirect immunofluorescence assay. |
| Databáze: | OpenAIRE |
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