Sarcoidosis presenting as metastatic lymphadenopathy in breast cancer

Autor: Stephen Chiang, Mary R. Schwartz, Mani Akhtari, Bin S. Teh, Jorge R. Quesada
Rok vydání: 2014
Předmět:
Zdroj: Clinical breast cancer. 14(5)
ISSN: 1938-0666
Popis: Sarcoidosis is a systemic, granulomatous disorder that affects the lungs and mediastinal lymph nodes in most patients. Areas affected by sarcoidosis can exhibit F-fluoro2-deoxy-D-glucose avidity on positron emission tomography (PET). We report the case of a 47-year-old woman with T2N0 cancer of the right breast who was initially diagnosed as stage IV because of multiple areas of mediastinal and supraclavicular PET-positive lymphadenopathy. Biopsy of a supraclavicular lymph node showed noncaseating granulomas, consistent with sarcoidosis, leading to appropriate treatment for her stage IIA disease. The imaging characteristics of sarcoidosis and its possible implications in staging and diagnosis of malignancy, more specifically in breast cancer patients, are discussed herein.
Databáze: OpenAIRE