Trp-ing upon new repressors
| Autor: | Andreas K. Brödel, Mark Isalan |
|---|---|
| Přispěvatelé: | Commission of the European Communities, Wellcome Trust, Biotechnology and Biological Sciences Research Council (BBSRC) |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Biochemistry & Molecular Biology Science & Technology Gene Circuits 0601 Biochemistry And Cell Biology Repressor Cell Biology Computational biology Biology Directed evolution 0304 Medicinal And Biomolecular Chemistry Repressor Proteins 03 medical and health sciences 030104 developmental biology Bacterial Proteins REPLICATION Tryptophan repressor Life Sciences & Biomedicine Molecular Biology Transcription factor Phylogeny Transcription Factors |
| Zdroj: | Nature Chemical Biology. 14:328-329 |
| ISSN: | 1552-4469 1552-4450 |
| DOI: | 10.1038/s41589-018-0012-9 |
| Popis: | Bioengineers have used directed evolution to generate a new family of synthetic transcription factors based on the tryptophan repressor. The evolved repressor family enables researchers to build new gene circuits for biomedical applications. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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