Risk Assessment at 11–14-Week Antenatal Visit: A Tertiary Referral Center Experience from South India

Autor: Akhila Vasudeva, Sapna Vinit Amin, Lavanya Rai, Pratap Kumar, Rajeshwari G Bhat, Asha Kamath, Anusha Vellamkondu
Rok vydání: 2017
Předmět:
Zdroj: The Journal of Obstetrics and Gynecology of India. 67:421-427
ISSN: 0975-6434
0971-9202
Popis: Present study carried out in a tertiary referral hospital in South India attempts to determine the predictive value of integrated screening at 11–14-week antenatal visit. To determine the detection rate of fetal abnormalities at 11–14 weeks and also to predict the placental dysfunction disorders based on early integrated evaluation. Integrated screening performed on 440 women between 11 and 14 weeks, including detailed maternal history [medical history, bad obstetric history (BOH)], body mass index (BMI), mean arterial pressure (MAP), detailed ultrasound and maternal serum biochemistry as part of combined first-trimester screening for aneuploidy. There were two proven Down’s syndrome foetuses; both detected with combined screening test. There were 12 fetuses with major anomalies, out of whom 7 (58.3%) detected in 11–14-week scan. Among 440, 114 pregnancies (25.9%) developed complications in pregnancy, including 33 (7.5%) gestational hypertension, 8 (1.8%) pre-eclampsia, 41 (9.38%) SGA, 13 (2.9%) abortions, 22 (5%) indicated and 9 (2.04%) spontaneous preterm deliveries, 38 (8.63%) GDM and 3 (0.6%) stillbirth/IUD. Among the risk factors, age >35 years, BMI >23 kg/m2, BOH, MAP >105 mmHg and PAPP-A
Databáze: OpenAIRE
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