Bactericidal activity of peripheral blood neutrophils during the oestrous cycle and early pregnancy in the mare
| Autor: | P. L. Sertich, M. C. Garcia, Robert M. Kenney, P. J. Strzemienski, R. M. Dyer |
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| Rok vydání: | 1987 |
| Předmět: |
Blood Bactericidal Activity
Staphylococcus aureus Embryology medicine.medical_specialty Neutrophils media_common.quotation_subject Prostaglandin Biology chemistry.chemical_compound Endocrinology Estrus Pregnancy Internal medicine medicine Animals Horses Incubation Ovulation media_common Colony-forming unit Estrous cycle Obstetrics and Gynecology Horse Cell Biology medicine.disease Reproductive Medicine chemistry Pregnancy Animal Female |
| Zdroj: | Reproduction. 80:289-293 |
| ISSN: | 1741-7899 1470-1626 |
| DOI: | 10.1530/jrf.0.0800289 |
| Popis: | The oestrous cycles of 20 mixed-breed mares were synchronized with daily injections of 10 mg oestradiol-17 beta and 150 mg progesterone given i.m. for 10 days. On the 10th day, 10-15 mg prostaglandin F-2 alpha was administered i.m. to induce oestrus. Neutrophils were isolated from jugular blood on the 2nd or 3rd day of oestrus, Days 5 and 7 after ovulation or during early pregnancy (Days 18-34 of pregnancy). Neutrophils were challenged with Staphylococcus aureus and their bactericidal activity examined after 30 and 120 min of incubation for a reduction of colony forming units. Bactericidal activity increased with the time of incubation (P less than 0.01) but did not differ for the oestrous cycle or pregnancy (P greater than 0.05). |
| Databáze: | OpenAIRE |
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