Gamma Interferon and Interleukin-10 Gene Expression in Synovial Tissues from Patients with Early Stages of Chlamydia -Associated Arthritis and Undifferentiated Oligoarthritis and from Healthy Volunteers

Autor:	Alan P. Hudson, Hervé C. Gérard, Patrick J. Branigan, Thurayya Arayssi, H. Ralph Schumacher, Shigeru Kotake, John H. Klippel, Cheryl Yarboro, Ronald L. Wilder
Rok vydání:	1999
Předmět:	Adult DNA Bacterial Male Pathology medicine.medical_specialty Immunology Gene Expression Arthritis Biology Microbiology Interferon-gamma Mice Gene expression medicine Animals Humans Interferon gamma RNA Messenger Chlamydia Pneumonitis Host Response and Inflammation Arthritis Infectious Oligoarthritis Synovial Membrane Chlamydia Infections Middle Aged medicine.disease Interleukin-10 Interleukin 10 Infectious Diseases medicine.anatomical_structure Case-Control Studies Cytokines Female Parasitology Synovial membrane medicine.drug
Zdroj:	Infection and Immunity. 67:2682-2686
ISSN:	1098-5522 0019-9567
Popis:	Genetically determined differences in interleukin-10 (IL-10) and gamma interferon (IFN-γ) responses in mice correlate with clearance of Chlamydia pneumonitis infection. We measured the synovial expression of IL-10 and IFN-γ and additional cytokine genes in patients who had recent-onset Chlamydia -associated arthritis (Chl-AA). IL-10 and IFN-γ mRNA were relatively abundant in recent-onset Chl-AA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7ca812411033556dd60285c4b3b16f https://doi.org/10.1128/iai.67.5.2682-2686.1999 Zobrazit plný text záznamu