Cartilage destruction in small joints by rheumatoid arthritis: assessment of fat-suppressed three-dimensional gradient-echo MR pulse sequences in vitro
| Autor: | M. P. Hauer, M. Langer, M. Uhl, K.-H. Allmann, Walter Conca, C. Ihling |
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| Rok vydání: | 1998 |
| Předmět: |
Cartilage
Articular Metatarsophalangeal Joint musculoskeletal diseases Hyalin Pathology medicine.medical_specialty Arthritis Metatarsophalangeal joints Pilot Projects Sensitivity and Specificity Arthroplasty Arthritis Rheumatoid Metacarpophalangeal Joint Bone Marrow Image Processing Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Arthroplasty Replacement Aged business.industry Hyaline cartilage Cartilage Metacarpophalangeal joint Middle Aged medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Adipose Tissue Rheumatoid arthritis Orthopedic surgery Cortical bone business Nuclear medicine |
| Zdroj: | Skeletal Radiology. 27:677-682 |
| ISSN: | 1432-2161 0364-2348 |
| Popis: | Purpose. To assess the accuracy of different MR sequences for the detection of articular cartilage abnormalities in rheumatoid arthritis. Design and patients. Ten metacarpophalangeal joints and 10 metatarsophalangeal joints (specimens from arthritis patients undergoing ablative joint surgery) were examined with a fat-suppressed (FS) 3D FLASH, a FS 3D FISP, a FS 2D fast spin-echo T2-weighted, and a 2D FS spin-echo T1-weighted sequence. Each cartilage lesion and each cortical lesion was graded from 0 to 4 (modified Outerbridge staging system). Subsequently, the results of each sequence were compared with the macroscopic findings and statistically tested against each other. Results. The study shows that 3D gradient-echo sequences with fat suppression were best for imaging and grading of cartilage lesions in arthritis of the small joints of the hands and feet. Using 3D techniques, all grade 2, grade 3, and grade 4 lesions of cartilage or cortical bone were detected. Conclusion. FS 3D gradient-echo techniques were best for the detection and grading of hyaline cartilage and subchondral bone lesions in rheumatoid arthritis. MRI has a great potential as an objective method of evaluating cartilage damage and bone erosions in rheumatoid arthritis. |
| Databáze: | OpenAIRE |
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