The effect of endovenous laser ablation on restless legs syndrome
| Autor: | C A Hayes, J Carlow, K R Hamby, J R Kingsley |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Severity of Illness Index Cohort Studies Sodium Tetradecyl Sulfate Varicose Veins Restless Legs Syndrome Surveys and Questionnaires mental disorders Severity of illness Varicose veins Sclerotherapy Medicine Humans Restless legs syndrome business.industry Endovenous laser treatment General Medicine Middle Aged medicine.disease Sclerosing Solutions Sodium tetradecyl sulfate Surgery Treatment Outcome Venous Insufficiency Cohort Female Laser Therapy medicine.symptom Cardiology and Cardiovascular Medicine business Cohort study medicine.drug Follow-Up Studies |
| Zdroj: | Phlebology. 23(3) |
| ISSN: | 0268-3555 |
| Popis: | Objectives Venous disease was proposed as a cause of restless legs syndrome (RLS) by Dr Karl A Ekbom in 1944, but has since remained largely unexplored. This study examines the effect of endovenous laser ablation (ELA) in patients with concurrent RLS and duplex-proven superficial venous insufficiency (SVI). Methods Thirty-five patients with moderate to very severe RLS (as defined by the 2003 National Institute of Health (NIH) RLS criteria) and duplex-proven SVI completed an international RLS rating scale questionnaire (IRLS) and underwent standard duplex examination to objectively measure the baseline severity of their conditions. They were separated into non-operative and operative cohorts. The operative cohort underwent ELA of refluxing superficial axial veins using the CoolTouch CTEV 1320 nm laser and ultrasound-guided sclerotherapy of the associated varicose veins with foamed sodium tetradecyl sulphate (STS). All patients then completed a follow-up IRLS questionnaire. Baseline and follow-up IRLS scores were compared. Results Operative correction of the SVI decreased the mean IRLS score by 21.4 points from 26.9 to 5.5, corresponding to an average of 80% improvement in symptoms. A total of 89% of patients enjoyed a decrease in their score of ≥15 points. Fifty-three percent of patients had a follow-up score of ≤5, indicating their symptoms had been largely alleviated and 31% had a follow-up score of zero, indicating a complete relief of RLS symptoms. Conclusions ELA of refluxing axial veins with the CTEV 1320 nm laser and foamed STS sclerotherapy of associated varicosities alleviates RLS symptoms in patients with SVI and moderate to very severe RLS. Recommendations SVI should be ruled-out in all patients with RLS before initiation or continuation of drug therapy. |
| Databáze: | OpenAIRE |
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