Normal pancreatic volume in adults is influenced by visceral fat, vertebral body width and age
| Autor: | Lida Changiziyan Frederiksen, Jens Brøndum Frøkjær, Asbjørn Mohr Drewes, Esben Bolvig Mark, Johannes Peter Kipp, Søren Schou Olesen |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Pancreatic disease Urology Pancreatic volume Context (language use) Intra-Abdominal Fat Gastroenterology Body composition 030218 nuclear medicine & medical imaging 03 medical and health sciences Young Adult 0302 clinical medicine Age Segmentation Sex Factors Bayesian multivariate linear regression Internal medicine Medicine Humans Radiology Nuclear Medicine and imaging Human height Computed tomography Pancreas Aged Retrospective Studies Aged 80 and over Radiological and Ultrasound Technology business.industry Age Factors Gender Organ Size Hepatology Anthropometry Middle Aged medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis Cohort Body Composition Female business Tomography X-Ray Computed |
| Zdroj: | Kipp, J P, Olesen, S S, Mark, E B, Frederiksen, L C, Drewes, A M & Frøkjær, J B 2019, ' Normal pancreatic volume in adults is influenced by visceral fat, vertebral body width and age ', Abdominal Radiology, vol. 44, no. 3, pp. 958–966 . https://doi.org/10.1007/s00261-018-1793-8 |
| ISSN: | 2366-0058 |
| DOI: | 10.1007/s00261-018-1793-8 |
| Popis: | Objectives: The aim was to describe the pancreatic volume (PV) in a cohort of subjects with no prior history of pancreatic disease, and to explore the relationship between PV and conventional two-point measurements of the pancreas. Associations between PV, gender, age, abdominal body composition, and human height were explored as well. Methods: CT scans from 204 trauma patients (20–80 years, 100 males) were evaluated. PV was measured with semi-automatic segmentation. Standardized two-point measurements of the pancreas were obtained together with L1 vertebral body size (a proxy for human height) and abdominal body composition. Associations between PV and the other parameters were explored using uni- and multivariate linear regression. Results: The mean PV was 77.9 ± 21.7(SD) cm 3 with an interindividual variability from 18.8 to 139.8 cm 3 . The transversal diameter of the pancreatic head showed the strongest correlation to PV (r = 0.500, p < 0.001). Age, width of the L1 vertebral body, and visceral fat cross-sectional area were all independently associated with PV (all p < 0.001), while no independent association was seen for gender (p = 0.441). Conclusions: The pancreatic volume is subject to a large interindividual variability and is associated with age, human height and body composition, while gender had no independent influence on the pancreatic volume. Thus, future studies using PV as an outcome parameter should be evaluated in the context of anthropometric profiles. |
| Databáze: | OpenAIRE |
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