Small-bowel myeloid sarcoma: Report of a case with atypical presentation
| Autor: | Giovanni Serio, Carlo M. Girelli, Marilù Latargia, Alessandra Aguzzi, Valentina Carsenzuola |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Granulocytic sarcoma urologic and male genital diseases Acute leukaemia Article law.invention Capsule endoscopy law hemic and lymphatic diseases Myeloid sarcoma medicine MS myeloid sarcoma SBCE small bowel capsule endoscopy business.industry digestive oral and skin physiology Chloroma medicine.disease digestive system diseases Bowel obstruction Small-bowel Surgery Radiology Presentation (obstetrics) business AML acute myeloid leukaemia |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | INTRODUCTIONSmall-bowel myeloid sarcoma is rare. Acute bowel obstruction is its usual clinical presentation.PRESENTATION OF CASEWe report a case of small-bowel myeloid sarcoma that occurred in a 64-year-old woman who presented chronic secretory diarrhoea, hypokalaemia, and weight loss. Immature white blood cells in a peripheral smear and small-bowel capsule endoscopic features were the main diagnostic clues. The patient experienced capsule retention and developed acute bowel obstruction. Urgent laparotomy showed a stricturing ileal mass and pathology of the resected bowel specimen unveiled a CD34+, CD117+, and myeloperoxidase-positive myeloid sarcoma. The diarrhoea promptly resolved after surgery, and the patient is now undergoing chemotherapy.DISCUSSIONSecretory diarrhoea can be the first manifestation of small-bowel myeloid sarcoma. Capsule endoscopy may provide a diagnostic clue, but it can trigger an acute bowel obstruction. Differential diagnosis of the pathologic specimen may be difficult and a high suspicion index of is mandatory to perform immunophenotyping to determine the correct management.CONCLUSIONChronic diarrhoea with alarm features can be the first manifestation of small-bowel myeloid sarcoma. |
| Databáze: | OpenAIRE |
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