Relationship between the first pass effect and the platelet-lymphocyte ratio in acute ischemic stroke
| Autor: | Ahmet Ergin Capar, Orkun Sarioglu, Pelin Topkaya, Demet Funda Bas Sokmez, Umit Belet |
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| Rok vydání: | 2020 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty 030204 cardiovascular system & hematology Endovascular therapy Brain Ischemia 03 medical and health sciences First pass effect 0302 clinical medicine Internal medicine medicine Humans In patient Lymphocytes Acute ischemic stroke Aged Ischemic Stroke Retrospective Studies Platelet lymphocyte ratio business.industry Middle Aged Clinical neurology Stroke Ischemic stroke Cardiology Female business 030217 neurology & neurosurgery |
| Zdroj: | Interv Neuroradiol |
| ISSN: | 2385-2011 1591-0199 |
| DOI: | 10.1177/1591019920976251 |
| Popis: | Purpose The aim of this study was to evaluate the relationship between platelet-lymphocyte ratio (PLR) and first pass effect (FPE) in patients with acute ischemic stroke (AIS). Our secondary goal was to investigate other laboratory, demographic or technical parameters that may be related to FPE and to search for independent predictors of FPE. Materials and methods Patients who underwent mechanical thrombectomy (MT) in our hospital between January 2017 and February 2020 were reviewed. Patients were divided into two groups: FPE and non-FPE. Demographic features, laboratory parameters, pretreatment imaging and clinical features, angiographic and clinical outcomes were recorded and compared between the two groups. Logistic regression analysis was performed to analyze the independent predictors and a predictive model was produced for demonstrating the possibility to achieve FPE. Results The study consisted of 83 patients (37 female, 46 male; mean age 62.69 ± 15.16) who were treated by MT. FPE was achieved in 32 patients (32/83, 38.6%). PLR was higher in the non-FPE group (195.35 ± 101.49) when compared to the FPE group (103.17 ± 37.06). A PLR value of Conclusions High levels of PLR were associated with the failure of FPE. High values of PLR may be considered as a negative predictor for FPE achievement prior to MT in patients with AIS. |
| Databáze: | OpenAIRE |
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