Quantitative Transcranial Sonography Evaluation of Substantia Nigra Hyperechogenicity Is Useful for Predicting Levodopa-Induced Dyskinesia in Parkinson Disease

Autor: Jia-Hui Yan, Kai Li, Yi-Lun Ge, Wen Li, Pu-Zhi Wang, Hong Jin, Jin-Ru Zhang, Jing Chen, Fen Wang, Ya-Ping Yang, Ying-Chun Zhang, Dan Li, Cheng-Jie Mao, Chun-Feng Liu
Rok vydání: 2022
Předmět:
Zdroj: Ultrasound in medicinebiology. 49(2)
ISSN: 1879-291X
Popis: Levodopa-induced dyskinesia (LID) is a common motor complication in Parkinson disease (PD). Abnormal substantia nigra hyperechogenicity (SN+), detected by transcranial sonography (TCS), plays an important role in the differential diagnosis of PD. The purpose of this study was to investigate the predictive performance of quantitative SN+ evaluations for LID. Five hundred sixty-two individuals were included in our analysis, and 198 individuals were followed up. These individuals were divided into two groups at baseline: the PD with LID (PD+LID) group and the PD without LID (PD-LID) group. The association between total hyperechogenic area of the SN on both sides (SN
Databáze: OpenAIRE