A case report of mantle cell lymphoma presenting as intussuscepting colon mass
| Autor: | Amy Deeken, Kyle Reilly, Elena Baker, Brandon M Smith, Adrian G Dan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Colonoscopy Article 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Intussusception (medical disorder) Case report Medicine Ascending colon Primary GI lymphoma Chemotherapy Mantle cell lymphoma medicine.diagnostic_test business.industry medicine.disease digestive system diseases Colo-colonic intussusception Lymphoma medicine.anatomical_structure 030220 oncology & carcinogenesis Abdomen 030211 gastroenterology & hepatology Surgery Radiology Presentation (obstetrics) business |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | Highlights • Primary gastrointestinal lymphomas rarely present as a single colonic mass. • This is a case report of a single mass colonic mantle cell lymphoma causing a colon-colonic intussusception. • Timely diagnosis and treatment of mantle cell lymphoma is critical. • Case represents a patient whose treatment plan was unexpectedly altered from surgery after a biopsy. Introduction Mantle Cell Lymphoma (MCL) is a non-Hodgkin lymphoma accounting for 2.5% of lymphoid neoplasms in the United States. Primary gastrointestinal (GI) lymphomas account for 1–4% of all GI malignancies, with few reports of primary mantle cell lymphoma presenting as a single colonic mass and none to our knowledge with colon-colonic intussusception as the presenting finding. Accurate and timely diagnosis is imperative because MCL has rapid progression and early chemotherapeutic intervention results in improved patient outcomes. This work is reported in line with the SCARE criteria [1] for case report publication. Presentation of case A 61-year-old male presented with 1 month history of nonspecific right sided abdominal pain. Computed Tomography (CT) of the abdomen identified an intussuscepting mass in the proximal ascending colon and an additional 8 mm hepatic lesion. Colonoscopy identified a large mass in the corresponding area of colon identified on CT. Histology and immunohistochemistry of biopsied specimen diagnosed MCL. Discussion Planned surgical intervention was deferred and the patient was referred for oncologic treatment. We report the first case to our knowledge of MCL presenting as colon-colonic intussusception and discuss the work-up of this rare lymphoma that clinicians may be required to diagnose and manage. Conclusion This report serves as a reminder to maintain a broad differential inclusive of uncommon diseases and unanticipated pathology. Practicing with a thorough understanding of medical principles and clinical acumen is essential for optimal patient care and, as demonstrated in this case, preventing a potentially unnecessary surgical intervention thus delaying appropriate chemotherapy. |
| Databáze: | OpenAIRE |
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