Renal Hemodynamic Response to the Creation of Vascular Access in Patients with End-Stage Renal Disease
| Autor: | Richard L. Morrissey, Eugene D. Silverman, Susan T. Crowley, William M. Yudt, Przemyslaw Hirszel |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Renal function Critical Care and Intensive Care Medicine End stage renal disease Arteriovenous Shunt Surgical Internal medicine medicine Humans Aged Kidney business.industry Hemodynamics Effective renal plasma flow General Medicine Middle Aged Surgery Filtration fraction medicine.anatomical_structure Nephrology Cardiology Vascular resistance Kidney Failure Chronic Female Hemodialysis business Glomerular hyperfiltration Glomerular Filtration Rate |
| Zdroj: | Renal Failure. 17:589-593 |
| ISSN: | 1525-6049 0886-022X |
| DOI: | 10.1080/0886022x.1995.12098270 |
| Popis: | To evaluate the possibility that the placement of arteriovenous anastomosis (a/v a) may lead to the attenuation of glomerular hyperfiltration, we studied 5 nondiabetic patients before and after creation of vascular access for hemodialysis. Patients received no EPO and antihypertensive therapy was discontinued 24 h before each study. Cardiac output (CO) and a/v a flow rates were measured by Doppler echo, and GFR and ERPF by plasma decay curves of Tc99m DTPA and 131I-hippuran, respectively. Other parameters were calculated by standard formulas. Augmentation of CO and decrease in systemic vascular resistance occurred in all patients (p = 0.05), yet renal findings were less predictable since only three patients showed a decrease in renal vascular resistance and filtration fraction post a/v a. Thus, there is a discordant pattern of renal hemodynamic response to the creation of a/v a in end-stage renal disease and further studies are needed to better define the subset of patients who are prone to renal vasodilation after the placement of a/v a. |
| Databáze: | OpenAIRE |
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