How to report incidental findings from population whole-body MRI: view of participants of the German National Cohort
Autor: | Fabian Bamberg, Christoph Neumann, Rudolf Kaaks, Anja Granitza, Oyunbileg von Stackelberg, Sabine Weckbach, Hans-Ulrich Kauczor, Robert C. Bertheau, Henry Völzke, Nicole Werner, Pia Erdmann, Christopher L. Schlett, Sonja Selder, Peter Hegedüs |
---|---|
Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_specialty Quality management Population Pilot Projects 030218 nuclear medicine & medical imaging National cohort German 03 medical and health sciences 0302 clinical medicine Germany Surveys and Questionnaires Epidemiology medicine Humans Radiology Nuclear Medicine and imaging Whole Body Imaging education First impression (psychology) Neuroradiology education.field_of_study Incidental Findings Descriptive statistics business.industry Reproducibility of Results General Medicine Middle Aged Magnetic Resonance Imaging language.human_language 030220 oncology & carcinogenesis Family medicine language Feasibility Studies Female Radiology business Follow-Up Studies |
Zdroj: | European radiology. 29(11) |
ISSN: | 1432-1084 |
Popis: | In the German National Cohort (GNC), 30,000 individuals are examined with whole-body MRI (wbMRI), of which about 3000 participants are expected to receive an incidental finding (IF) disclosure. In order to get feedback from participants and to evaluate the IF-management procedure of the wbMRI substudy, a follow-up questionnaire was developed. This single-center pilot trial was aimed to get a first impression on feasibility reproducibility and validity of such a survey in order to take necessary adjustments before initiating the survey among several thousand participants. The questionnaires were sent out in test–retest manner to 86 participants who received a wbMRI examination in January–February 2016 at the imaging center in Neubrandenburg. The ratio of participants with and without IF notification was 1:1. Descriptive statistics was performed. A first response of 94% and completion proportion of 99% were achieved. Participants were satisfied with the examination procedure. Ninety-five percent of participants considered it very important to receive notification of IFs. Participants reported minimal stress levels while waiting for a possible IF notification letter, but high stress levels when an IF letter was received. Phrasing of the IF reports was rated in 97% as well understandable and in 55% as beneficial to health status. This questionnaire will serve researchers within the GNC as a fundamental instrument not only for quality management analyses but also for the investigation of still unacknowledged scientific and ethical questions contributing to evidence-based guidelines concerning the complex approach to IFs in future population-based imaging. • Evidence-based guidelines for reporting incidental findings in population whole-body MRI are lacking. • Pilot-testing of a questionnaire for the evaluation of practical and ethical aspects of the procedure to report incidental findings in the German National Cohort shows a high level of acceptance and high return rate by participants. • Participants reported minimal stress levels while waiting for a possible incidental finding notification letter, which increased significantly, when such a letter was received. |
Databáze: | OpenAIRE |
Externí odkaz: |