Expression of a neural cell adhesion molecule serum fragment is depressed in autism
| Autor: | Hemmens Se, Plioplys Av, Regan Cm |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Antiserum
Adult Male Adolescent Chemistry Cell Adhesion Molecules Neuronal Enzyme-Linked Immunosorbent Assay medicine.disease Molecular biology Psychiatry and Mental health nervous system Gene Expression Regulation Schizophrenia Reference Values Immunology medicine Autism Humans Neural cell adhesion molecule Female Neurology (clinical) Autistic Disorder Child |
| Zdroj: | The Journal of neuropsychiatry and clinical neurosciences. 2(4) |
| ISSN: | 0895-0172 |
| Popis: | The level of a neural cell adhesion molecule (NCAM) serum fragment in autism was determined by using an antiserum prepared with immunoaffinity purified mouse NCAM. Autistic patients (N = 16) had statistically significantly decreased serum NCAM levels compared with age-matched controls (p less than 0.0005). This observation could not be attributed to a medication-induced effect. Depressed serum NCAM levels in autism are distinct from schizophrenia, in which serum NCAM levels are elevated. |
| Databáze: | OpenAIRE |
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