Prevalence of Physical Frailty: Results from the DO-HEALTH Study
| Autor: | Gregor Freystaetter, S. Guyonnet, Michael Gagesch, Dieter Felsenberg, Andreas Egli, Heike A. Bischoff-Ferrari, Patricia O. Chocano-Bedoya, J. A. Kanis, Reto W. Kressig, Endel J. Orav, J. A. P. DaSilva, A. Sadlon, René Rizzoli, Lauren A Abderhalden, Michael Blauth |
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| Přispěvatelé: | University of Zurich, Gagesch, Michael |
| Rok vydání: | 2021 |
| Předmět: |
Complete data
11221 Clinic for Geriatric Medicine Frail Elderly Population prevalence 610 Medicine & health 2700 General Medicine frailty Logistic regression Health outcomes 03 medical and health sciences 0302 clinical medicine 360 Social problems & social services Medicine Humans 030212 general & internal medicine education Geriatric Assessment Aged education.field_of_study clinical trials Geriatrics gerontology business.industry Mean age General Medicine Frailty phenotype community-dwelling Cross-Sectional Studies Female epidemiology business 030217 neurology & neurosurgery Demography |
| Zdroj: | Journal of Frailty & Aging Gagesch, M.; Chocano-Bedoya, P. O.; Abderhalden, L.A.; Freystaetter, G.; Sadlon, A.; Kanis, J.A.; Kressig, R.W.; Guyonnet, S.; DaSilva, J.A.P.; Felsenberg, D.; Rizzoli, R.; Blauth, M.; Orav, E.J.; Egli, A.; Bischoff-Ferrari, H.A. (2021). Prevalence of Physical Frailty: Results from the DO-HEALTH Study (In Press). Journal of Frailty & Aging Springer 10.14283/jfa.2021.18 |
| ISSN: | 2273-4309 |
| DOI: | 10.14283/jfa.2021.18 |
| Popis: | Background Frailty is a geriatric syndrome associated with multiple negative health outcomes. However, its prevalence varies by population and instrument used. We investigated frailty and pre-frailty prevalence by 5 instruments in community-dwelling older adults enrolled to a randomized-controlled trial in 5 European countries. Methods Cross-sectional baseline analysis in 2,144 DO-HEALTH participants recruited from Switzerland, Austria, France, Germany, and Portugal with complete data for frailty. Frailty status was assessed by the Physical Frailty Phenotype [PFP], SOF-Frailty Index [SOF-FI], FRAIL-Scale, SHARE-Frailty Instrument [SHARE-FI], and a modified SHARE-FI, and compared by country, age, and gender. Logistic regression was used to determine relevant factors associated with frailty and pre-frailty. Results Mean age was 74.9 (��4.4) years, 61.6% were women. Based on the PFP, overall frailty and pre-frailty prevalence was 3.0% and 43.0%. By country, frailty prevalence was highest in Portugal (13.7%) and lowest in Austria (0%), and pre-frailty prevalence was highest in Portugal (57.3%) and lowest in Germany (37.1%). By instrument and overall, frailty and pre-frailty prevalence was highest based on SHARE-FI (7.0% / 43.7%) and lowest based on SOF-FI (1.0% / 25.9%). Frailty associated factors were residing in Coimbra (Portugal) [OR 12.0, CI 5.30���27.21], age above 75 years [OR 2.0, CI 1.17���3.45], and female gender [OR 2.8, CI 1.48���5.44]. The same three factors predicted pre-frailty. Conclusions Among relatively healthy adults age 70 and older enroled to DO-HEALTH, prevalence of frailty and pre-frailty differed significantly by instrument, country, gender, and age. Among instruments, the highest prevalence of frailty and pre-frailty was documented by the SHARE-FI and the lowest by the SOF-FI. |
| Databáze: | OpenAIRE |
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