Porcine sensitized lymph node cells (immunotherapy) and attenuated irradiation for infiltrative transitional cell carcinoma of bladder
| Autor: | Abraham T.K. Cockett, P. A. Di Sant'agnese, Derek J. Hamlin, Henry Keys |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Swine Urology medicine.medical_treatment Cystectomy Biopsy medicine Carcinoma Animals Humans Eosinophilia Stage (cooking) Lymph node Aged Carcinoma Transitional Cell medicine.diagnostic_test business.industry Radiotherapy Dosage Immunotherapy Middle Aged medicine.disease Transitional cell carcinoma medicine.anatomical_structure Urinary Bladder Neoplasms Female Lymph Nodes medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Urology. 19:593-597 |
| ISSN: | 0090-4295 |
| DOI: | 10.1016/0090-4295(82)90006-1 |
| Popis: | Thirty-four patients with infiltrative bladder carcinoma, Stage B2C or higher were treated with immunotherapy and irradiation. Seventeen patients are alive, and 17 have succumbed to their disease. Eight patients underwent cystectomy after immunotherapy and irradiation; 6 of 8 are alive and well at the present time. The technique of immunotherapy is outlined. New methodology for sequential CT scans and scheduled bladder biopsies is mentioned. The 17 patients have survived twelve to sixty-nine months after immunotherapy and irradiation. Downstaging is demonstrated based on sequential CT scans of the bony pelvis and histologic biopsy. The biopsies reveal eosinophilia and multinucleated giant cells, a specific response to immunotherapy. A prospective randomized study will be initiated. |
| Databáze: | OpenAIRE |
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