Identification of human T-cell lymphotropic virus infection in a semi-isolated Afro-Brazilian quilombo located in the Marajó Island (Pará, Brazil)
| Autor: | Marluísa de Oliveira Guimarães Ishak, Vânia Nakauth Azevedo, Antonio Carlos Rosário Vallinoto, Fernanda Andreza de Pinho Lott Carvalhaes, Gemilson Soares Pontes, Nilton Akio Muto, João Farias Guerreiro, Ivina Giselle Lima Lopes, Ricardo Ishak, Sidney Santos, Luiz Fernando Almeida Machado |
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| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Male
human T-cell lymphotropic virus Quilombolas viruses lcsh:QR1-502 Pará - Estado Polymerase Chain Reaction Vírus 2 linfotrópico T humano lcsh:Microbiology law.invention law Marajó Island Child Polymerase chain reaction Aged 80 and over Human T-lymphotropic virus 1 Amazon rainforest Human T-lymphotropic virus 2 virus diseases Middle Aged HTLV-I Antibodies Child Preschool HTLV-I infections Female Enzyme immunoassays Brazil Adult Microbiology (medical) lcsh:Arctic medicine. Tropical medicine Adolescent lcsh:RC955-962 Blotting Western Black People Enzyme-Linked Immunosorbent Assay Biology Virus Humans Afro-Brazilian communities Aged Vírus linfotrópico de células T humanas tipo 1 Ilha de Marajó - PA Sequence Analysis DNA biology.organism_classification HTLV-I Infections Virology Amazônia brasileira HTLV-II Infections Nested polymerase chain reaction |
| Zdroj: | Repositório Institucional da UFPA Universidade Federal do Pará (UFPA) instacron:UFPA Repositório Institucional do INPA Instituto Nacional de Pesquisas da Amazônia (INPA) instacron:INPA Memórias do Instituto Oswaldo Cruz., Vol 101, Iss 1, Pp 103-105 (2006) |
| Popis: | Antibodies to human T-cell lymphotropic virus-1 and 2 (HTLV-1 and 2) were tested in 259 inhabitants (98 males and 161 females) of four villages of the Marajó Island (Pará, Brazil) using enzyme immunoassays (ELISA and Western blot). Types and subtypes of HTLV were determined by nested polymerase chain reaction (PCR) targeting the pX, env and 5´LTR regions. HTLV-1 infection was detected in Santana do Arari (2.06%) and Ponta de Pedras (1%). HTLV-2 was detected only in Santana do Arari (1.06%). Sequencing of the 5´LTR region of HTLV-1 and the phylogenetic analysis identified the virus as a member of the Cosmopolitan Group, subgroup Transcontinental. Santana do Arari is an Afro-Brazilian community and the current results represent the first report of HTLV-1 infection in a mocambo located in the Brazilian Amazon region. |
| Databáze: | OpenAIRE |
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