Profile of plasma N-terminal proBNP following acute myocardial infarction. Correlation with left ventricular systolic dysfunction
| Autor: | S Talwar, M C Campton, A M Mccullough, Leong L. Ng, David B. Barnett, Joan E. Davies, P. F. Downie, Iain B. Squire |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.drug_class Myocardial Infarction Nerve Tissue Proteins Ventricular Dysfunction Left Predictive Value of Tests Internal medicine Natriuretic Peptide Brain Blood plasma Natriuretic peptide Humans Medicine Myocardial infarction Protein Precursors Systole Aged Aged 80 and over Analysis of Variance business.industry Middle Aged Brain natriuretic peptide medicine.disease Peptide Fragments Echocardiography Predictive value of tests ACE inhibitor Cardiology Regression Analysis Myocardial infarction complications Female Cardiology and Cardiovascular Medicine business Biomarkers medicine.drug |
| Zdroj: | European Heart Journal. 21:1514-1521 |
| ISSN: | 0195-668X |
| DOI: | 10.1053/euhj.1999.2045 |
| Popis: | Aims The aims of this study were to describe the temporal pattern of plasma N-terminal pro-brain natriuretic peptide, to examine the optimum time of sampling and to compare plasma N-terminal pro-brain natriuretic peptide to clinical criteria in terms of identification of impaired left ventricular systolic function following acute myocardial infarction. Methods and Results Measurements of N-terminal pro-brain natriuretic peptide were made in 60 patients at 14–48h, 49–72h, 73–120h, 121–192h following myocardial infarction and at 6 weeks in survivors. Left ventricular wall motion index was assessed during hospitalization (WMI-1) and at 6 weeks (WMI-2). N-terminal pro-brain natriuretic peptide levels were elevated at all time points, to a greater extent in anterior compared to inferior infarction ( P |
| Databáze: | OpenAIRE |
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