The effect of heat stress on proliferation, synthesis of steroids, and gene expression of duck granulosa cells
Autor: | Chen Yang, Tian Yunbo, Shi-jian Chen, Huang Yunmao, Dan-ning Xu, Wen-jun Liu, Xin-liang Fu, Xue-bing Huang, Xiu-jin Li |
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Rok vydání: | 2021 |
Předmět: |
Ovulation
MMP1 Down-Regulation Gene Expression Transcriptome Aromatase Heat shock protein Gene expression Animals Hedgehog Proteins Cholesterol Side-Chain Cleavage Enzyme KEGG Gene Heat-Shock Proteins Cell Proliferation Granulosa Cells Estradiol Chemistry Gene Expression Regulation Developmental General Medicine Hedgehog signaling pathway Cell biology Gene expression profiling Ducks Female Matrix Metalloproteinase 3 Matrix Metalloproteinase 1 General Agricultural and Biological Sciences Chemokines CXC Heat-Shock Response Signal Transduction |
Zdroj: | Animal Science Journal. 92 |
ISSN: | 1740-0929 1344-3941 |
DOI: | 10.1111/asj.13617 |
Popis: | Granulosa cells (GCs) play an important role in the development of follicles. In this study, we investigate the impact of heat stress at 41°C and 43°C on duck GCs' proliferation and steroids secretion. And, the transcriptomic responses to heat treatment were examined using RNA-sequencing analysis. Digital gene expression profiling was used to screen and identify differentially expressed genes (fold change ≥ 2 and Q value |
Databáze: | OpenAIRE |
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