Conduction Abnormalities after Transcatheter Aortic Valve Implantation and Diastolic Dysfunction
| Autor: | Ofir Priesler, Yoav Michowitz, Ariel Finkelstein, Simon Biner |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Transcatheter aortic Treatment outcome Diastole 030204 cardiovascular system & hematology Tertiary Care Centers Transcatheter Aortic Valve Replacement 03 medical and health sciences Electrocardiography Ventricular Dysfunction Left 0302 clinical medicine Heart Conduction System Internal medicine medicine Humans Pharmacology (medical) 030212 general & internal medicine Pulmonary Wedge Pressure Israel Pulmonary wedge pressure Aged Aged 80 and over Conduction abnormalities medicine.diagnostic_test business.industry Follow up studies Treatment Outcome Echocardiography Cardiology Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Cardiology. 137(1) |
| ISSN: | 1421-9751 |
| Popis: | Objectives: Transcatheter aortic valve implantation (TAVI) is frequently associated with the development of conduction abnormalities. We assessed the effect of conduction abnormalities on diastolic function following TAVI. Methods: In total, 101 consecutive post-TAVI patients were included, each with echocardiographic follow-up at 1 and 6 months. Diastolic properties were correlated with the occurrence of a long PR interval and wide QRS, and their change from baseline. The measured diastolic parameters included E/A ratio, E wave deceleration time, E wave to e′ ratio, left atrial (LA) volume, and systolic pulmonary artery pressure (SPAP). The clinical outcome was all-cause mortality. Results: Overall, TAVI was associated with a consistent decrease in SPAP at the 1- and 6-month follow-up. LA volumes were increased at 1 month post-TAVI in patients with a wide compared to normal QRS (p = 0.03) and at 6 months in patients with a normal compared to prolonged PR (p = 0.03). PR prolongation above 40 ms was associated with lower SPAP at the 1- but not 6-month follow-up. Survival was not influenced by conduction abnormalities. Conclusions: TAVI is associated with a reduction in SPAP. A postprocedural wide QRS and normal PR interval may unfavorably influence the left-sided filling performance, resulting in an increased LA volume. Other diastolic parameters, as well as survival, are not significantly affected by postprocedural conduction abnormalities. |
| Databáze: | OpenAIRE |
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