Group B Streptococcus in a cohort of HIV-infected pregnant women: Prevalence of colonization, identification and antimicrobial susceptibility profile

Autor:	Maria Isabel Fragoso da Silveira Gouvêa, Maria José de Souza, Caio Augusto Santos Rodrigues, Sergio Eduardo Longo Fracalanzza, Guilherme Amaral Calvet, Beatriz Grinsztejn, Esau Joao, Jacqueline A. Menezes, Haroldo José de Matos, Ana Caroline N. Botelho, Maria Letícia Santos Cruz
Rok vydání:	2011
Předmět:	Adult Microbiology (medical) Serotype medicine.medical_specialty Erythromycin HIV Infections Microbial Sensitivity Tests Penicillins Group B Streptococcus agalactiae Pregnancy Streptococcal Infections Internal medicine Drug Resistance Bacterial Prevalence medicine Humans Pregnancy Complications Infectious Serotyping Antibiotic prophylaxis General Immunology and Microbiology Transmission (medicine) business.industry Clindamycin Infant Newborn Rectum Infant General Medicine Viral Load Virology Anti-Bacterial Agents CD4 Lymphocyte Count Cross-Sectional Studies Infectious Diseases Vagina Cohort Female business Viral load medicine.drug
Zdroj:	Scandinavian Journal of Infectious Diseases. 43:742-746
ISSN:	1651-1980 0036-5548
DOI:	10.3109/00365548.2011.585178
Popis:	Group B Streptococcus (GBS) is a leading cause of infectious morbidity in newborns. We describe the prevalence of GBS colonization and the serotypes and antibiotic susceptibility profiles of isolates obtained from a cohort of human immunodeficiency virus (HIV)-infected pregnant women. This was a cross-sectional study at a centre for the prevention of mother-to-child transmission of HIV. Vaginal and rectal swabs were collected at 35-37 weeks of gestation from 158 eligible women. GBS isolates were serotyped and antimicrobial susceptibility tests performed. Patient sociodemographic characteristics, CD4 counts and viral loads were abstracted from records. The overall anogenital prevalence of GBS colonization was 49/158 (31.0%): 40/158 (25.3%) for vagina, 19/158 (12.0%) for rectum and 10/158 (6.3%) for both. Predominant serotypes were Ib (34.9%) and Ia (25.6%). All were penicillin-susceptible. Two were resistant to erythromycin (4.0%) and one to clindamycin (2.0%). The colonization rate by GBS was high in this cohort. Serotype Ib was the most frequently identified.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3402081fd8340a0d10d019eaa258a1 https://doi.org/10.3109/00365548.2011.585178 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.