Airway hyper-responsiveness to mannitol provides a good evaluation of atopy in childhood asthma
| Autor: | Daniele Rapino, Anna Cingolani, S. Di Pillo, M. L. Marcovecchio, Marina Attanasi, Francesco Chiarelli, Alessandra Scaparrotta, N.P. Consilvio |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Adolescent Immunoglobulin E Severity of Illness Index Bronchial Provocation Tests Airway Hyper-Responsiveness Aspergillus fumigatus Cohort Studies Atopy medicine Humans Mannitol Child Asthma Childhood asthma biology business.industry General Medicine Allergens medicine.disease biology.organism_classification Pediatrics Perinatology and Child Health Immunology biology.protein Female Bronchial Hyperreactivity business Airway medicine.drug |
| Zdroj: | Acta Paediatrica. 104:718-723 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/apa.12968 |
| Popis: | Aim The relationship between airway hyper-responsiveness (AHR) and atopy has been previously investigated, but there are still some issues to be clarified. The aim of this study was to assess the link between AHR and mannitol and atopy in asthmatic children. Methods We evaluated 44 children with asthma, aged 6–16 years of age, using skin prick tests (SPTs), serum total and specific immunoglobulin E (IgE) levels and the mannitol challenge test (MCT). Results We found a good correlation between AHR to mannitol and specific IgE against Dermatophagoides pteronissinus (r = −0.66, p |
| Databáze: | OpenAIRE |
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