Facile access to optically active labdane-type diterpenes from (+)-manool. Synthesis of (+)-coronarin E, (+)-15,16-epoxy-8(17),13(16),14-labdatriene, and (+)-labda-8(17),13(Z)-diene-15,16-diol
Autor: | José E. Villamizar, Franklin Salazar, Eleonora Tropper, Juan Fuentes, Randolph Alonso |
---|---|
Rok vydání: | 2003 |
Předmět: |
Diene
Stereochemistry Diol Pharmaceutical Science Catalysis Analytical Chemistry Labdane chemistry.chemical_compound Coronarin E Drug Discovery Organic chemistry Nuclear Magnetic Resonance Biomolecular Pharmacology Molecular Structure Organic Chemistry Stereoisomerism Epoxy Optically active Complementary and alternative medicine chemistry visual_art visual_art.visual_art_medium Molecular Medicine Indicators and Reagents Diterpenes Oxidation-Reduction |
Zdroj: | Journal of natural products. 66(12) |
ISSN: | 0163-3864 |
Popis: | An efficient method for the synthesis of (+)-coronarin E (1), (+)-15,16-epoxy-8(17),13(16),14-labdatriene (2), and (+)-labda-8(17),13(Z)-diene-15,16-diol (3) from (+)-manool is described. |
Databáze: | OpenAIRE |
Externí odkaz: |