Proton Pump Inhibitors and Oncologic Treatment Efficacy: A Practical Review of the Literature for Oncologists
| Autor: | Taciana Sousa Mutao, Angel Ayumi Tome Uchiyama, Pedro Alexandre Ismael Amaral Silva, Denis S Shimba, Larissa Machado, Eliza Dalsasso Ricardo, Moisés de Souza Martins Lopes, Cheng T Yen, Jefferson Rios Pimenta, Renata D'Alpino Peixoto |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Scarce data
Oncologists medicine.medical_specialty business.industry Drug-drug interaction Neoplasms. Tumors. Oncology. Including cancer and carcinogens Proton Pump Inhibitors Review chemotherapy 030226 pharmacology & pharmacy Treatment efficacy 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis tyrosine kinase inhibitors medicine Humans Drug Interactions immunotherapy Intensive care medicine business Healthcare providers RC254-282 drug-drug interaction |
| Zdroj: | Current Oncology Current Oncology, Vol 28, Iss 76, Pp 783-799 (2021) |
| ISSN: | 1718-7729 |
| Popis: | Proton pump inhibitors (PPIs) are the most commonly used anti-acid drugs worldwide, including among cancer patients. However, drug-drug interactions between PPIs and other agents may lead to decreased drug absorption with possible reduced therapeutic benefit, or even increased toxicity. Unfortunately, only scarce data exist regarding the safety of concomitant PPI use with anti-cancer agents. We aim at reviewing current evidence on this possible interaction by dividing anti-cancer agents by class. Until further data is available, we encourage healthcare providers to limit unnecessary PPI overuse. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|