Treatable Vascular Risk and Cognitive Performance in Persons Aged 35 Years or Older
| Autor: | Gerbrand J. Izaks, Hanneke Joosten, Joris P. J. Slaets, M. E. A. Van Eersel, Ron T. Gansevoort |
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| Přispěvatelé: | RS: FHML non-thematic output, MUMC+: MA Medische Staf IC (9), Groningen Kidney Center (GKC), Cardiovascular Centre (CVC), Health Psychology Research (HPR) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Aging Longitudinal study Pediatrics medicine.medical_specialty Comorbidity Disease Neuropsychological Tests preventing cognitive impairment Risk Factors cardiovascular disease Diabetes mellitus medicine Humans Dementia Cognitive Dysfunction Longitudinal Studies Effects of sleep deprivation on cognitive performance METAANALYSES Cognitive performance Stroke Aged Netherlands Original Research Aged 80 and over DECLINE OUTCOMES Framingham Risk Score business.industry DEMENTIA longitudinal analysis ASSOCIATION Middle Aged CARE medicine.disease PREVENTION treatable vascular risk ALZHEIMERS-DISEASE Cardiovascular Diseases Cohort Female business INTERVENTION STROKE |
| Zdroj: | JPAD-Journal of prevention of alzheimers disease, 6(1), 42-49. Editions SERDI The journal of prevention of Alzheimer's disease, 6(1), 42-49. EDITIONS SERDI The Journal of Prevention of Alzheimer's Disease |
| ISSN: | 2426-0266 2274-5807 |
| Popis: | Background Poor cognitive performance is associated with high vascular risk. However, this association is only investigated in elderly. As neuropathological changes precede clinical symptoms of cognitive impairment by several decades, it is likely that cognitive performance is already associated with vascular risk at middle-age. Objectives To investigate the association of cognitive performance with treatable vascular risk in middle-aged and old persons. Design Longitudinal study with three measurements during follow-up period of 5.5 years. Setting City of Groningen, the Netherlands. Participants Cohort of 3,572 participants (age range, 35–82 years; mean age, 54 years; men, 52%). Exposure Treatable vascular risk as defined by treatable components of the Framingham Risk Score for Cardiovascular Disease at the first measurement (diabetes mellitus, smoking, hypercholesterolemia and hypertension). Measurements Change in cognitive performance during follow-up. Cognitive performance was measured with Ruff Figural Fluency Test (RFFT) and Visual Association Test (VAT), and calculated as the average of the standardized RFFT and VAT score per participant. Results The mean (SD) cognitive performance changed from 0.00 (0.79) at the first measurement to 0.15 (0.83) at second measurement and to 0.39 (0.82) at the third measurement (Ptrend |
| Databáze: | OpenAIRE |
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