Anti-nociceptive and anti-inflammatory activities of the methanolic extract of Parinari polyandra stem bark in rats and mice
| Autor: | O. F. Kunle, B. A. Chindo, P.B. Otsapa, H. O. Vongtau, Karniyus S. Gamaniel, I.E. Ngazal, J. Abbah |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.drug_class Pharmacognosy Anti-inflammatory Lethal Dose 50 Mice Drug Discovery medicine Animals Rats Wistar Hot plate test Rosaceae Pharmacology Analgesics biology Traditional medicine Plant Extracts Chemistry Anti-Inflammatory Agents Non-Steroidal Biological activity biology.organism_classification Parinari Rats Nociception Phytochemical Biochemistry visual_art Plant Bark visual_art.visual_art_medium Female Bark |
| Zdroj: | Journal of Ethnopharmacology. 90:115-121 |
| ISSN: | 0378-8741 |
| DOI: | 10.1016/j.jep.2003.09.038 |
| Popis: | The methanolic extract of the stem bark of Parinari polyandra (family Rosaceae) was investigated for possible anti-nociceptive and anti-inflammatory effects in mice and rats. Three models were used to study the extracts effects on nociception which were the acetic acid-induced abdominal constriction test, hot-plate method (both in mice) and the formalin test in rats. The anti-inflammatory effects were investigated employing the albumin-induced hind-paw oedema in rats. Results of the study revealed the extract to have significant (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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