Effect on neonatal oestrogen and hCG treatment on the genital organs of adult female rats
| Autor: | Zora Nikolić, Zdenka Blagojević, Verica Mrvić, I. Ivanov |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
hCG Uterus Ovary Biology Chorionic Gonadotropin Human chorionic gonadotropin 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Animals rat Sex organ Rats Wistar 030304 developmental biology 0303 health sciences Hcg treatment uterus General Veterinary Adult female Estradiol Histocytochemistry Genitalia Female Epithelium 3. Good health Rats medicine.anatomical_structure Endocrinology vagina Animals Newborn 030220 oncology & carcinogenesis Vagina ovary Female oestrogen |
| Zdroj: | Acta veterinaria Hungarica |
| ISSN: | 0236-6290 |
| Popis: | The ovaries and the uterine as well as vaginal mucous membranes of 80-, 180- and 365-day-old intact female rats and females neonatally treated with a single dose of oestrogen and repeated doses of human chorionic gonadotropin (hCG) were studied. Numerous follicles, interstitial cells and corpora lutea (CL) were present on the ovary of intact females from 80 up to 365 days of age. The number of primary and secondary follicles decreased in the intact female rats between Day 180 and Day 365 of life. On the ovaries of 180- and 365-day-old female rats neonatally treated with oestrogen, interstitial glandular cells and cystic follicles predominated. No CL were present on these ovaries. The height of epithelial cells of the uterine and vaginal mucous membranes increased in intact female rats from 80 to 365 days of age, whereas in oestrogen-treated females the height of epithelium decreased. From 80 up to 365 days of age, the height of epithelial cells of uterine and vaginal mucous membranes of rats neonatally treated with repeated doses of hCG was similar to that in the corresponding control animals. |
| Databáze: | OpenAIRE |
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