Plethysmographic dynamic indices predict fluid responsiveness in septic ventilated patients

Autor: M. Feissel, Julio Badie, Jean-Pierre Faller, Jean-Louis Teboul, Paolo Merlani, Karim Bendjelid
Rok vydání: 2007
Předmět:
Zdroj: Intensive Care Medicine, Vol. 33, No 6 (2007) pp. 993-9
ISSN: 1432-1238
0342-4642
Popis: Objectives: In septic patients, reliable non-invasive predictors of fluid responsiveness are needed. We hypothesised that the respiratory changes in the amplitude of the plethysmographic pulse wave (ΔPPLET) would allow the prediction of changes in cardiac index following volume administration in mechanically ventilated septic patients. Design: Prospective clinical investigation. Setting: An 11-bed hospital medical intensive care unit. Patients: Twenty-three deeply sedated septic patients mechanically ventilated with tidal volume ≥ 8 ml/kg and equipped with an arterial catheter and apulse oximetry plethysmographic sensor. Interventions: Respiratory changes in pulse pressure (ΔPP), ΔPPLET and cardiac index (transthoracic Doppler echocardiography) were determined before and after volume infusion of colloids (8 ml/kg). Measurements and main results: Twenty-eight volume challenges were performed in 23 patients. Before volume expansion, ΔPP correlated with ΔPPLET (r 2 = 0.71, p
Databáze: OpenAIRE