| Autor: |
Javier de Juan Bagudá, Juan J. Gavira Gómez, Marta Pachón Iglesias, Rocío Cózar León, Vanessa Escolar Pérez, Óscar González Fernández, Nuria Rivas Gándara, Josebe Goirigolzarri Artaza, Beatriz Díaz Molina, Alfonso Macías Gallego, Virgilio Martínez Mateo, Juan G. Martínez Martínez, Natalia Marrero Negrín, Gonzalo L. Alonso Salinas, Luis González Torres, Juan F. Delgado Jiménez, Paula Sánchez-Aguilera, Ernesto Díaz Infante, María F. Arcocha Torres, Laura Peña Conde, Ana B. Méndez Fernández, Nicasio Pérez Castellano, José M. Rubín López, Inés Madrazo Delgado, Manuel J. Fernández-Anguita, Pablo Ramos Ruiz, Olga Medina Moreno, David Cordero Pereda, Carlos de Diego Rus, Fernando Arribas Ynsaurriaga, Ignacio García Bolao, Rafael Salguero Bodes |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Revista espanola de cardiologia (English ed.). 75(9) |
| ISSN: |
1885-5857 |
| Popis: |
HeartLogic is a multiparametric algorithm incorporated into implantable cardioverter-defibrillators (ICD). The associated alerts predict impending heart failure (HF) decompensations. Our objective was to analyze the association between alerts and clinical events and to describe the implementation of a protocol for remote management in a multicenter registry.We evaluated study phase 1 (the investigators were blinded to the alert state) and phases 2 and 3 (after HeartLogic activation, managed as per local practice and with a standardized protocol, respectively).We included 288 patients from 15 centers. In phase 1, the median observation period was 10 months and there were 73 alerts (0.72 alerts/patient-y), with 8 hospitalizations and 2 emergency room admissions for HF (0.10 events/patient-y). There were no HF hospitalizations outside the alert period. In the active phases, the median follow-up was 16 (95%CI, 15-22) months and there were 277 alerts (0.89 alerts/patient-y); 33 were associated with HF hospitalizations or HF death (n=6), 46 with minor decompensations, and 78 with other events. The unexplained alert rate was 0.39 alerts/patient-y. Outside the alert state, there was only 1 HF hospitalization and 1 minor HF decompensation. Most alerts (82% in phase 2 and 81% in phase 3; P=.861) were remotely managed. The median NT-proBNP value was higher within than outside the alert state (7378 vs 1210 pg/mL; P.001).The HeartLogic index was frequently associated with HF-related events and other clinically relevant situations, with a low rate of unexplained events. A standardized protocol allowed alerts to be safely and remotely detected and appropriate action to be taken on them. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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