Postmortem analysis of invasive aspergillosis in a tertiary care hospital
| Autor: | D Aust, G. Ruckdeschel, A. Haas, M. Vogeser |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Autopsy Aspergillosis Organ transplantation Aspergillus fumigatus Hospitals University Immunocompromised Host Germany Internal medicine medicine Humans Mycosis Aged Retrospective Studies medicine.diagnostic_test biology business.industry Organ Transplantation General Medicine Hospital Bed Capacity 500 and over Middle Aged medicine.disease biology.organism_classification Surgery Latex fixation test Transplantation Infectious Diseases Bronchoalveolar lavage Female business Latex Fixation Tests |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 16:1-6 |
| ISSN: | 1435-4373 0934-9723 |
| DOI: | 10.1007/bf01575110 |
| Popis: | To estimate the incidence of fatal invasive aspergillosis in a 1500-bed tertiary-care hospital and to investigate the utility of laboratory diagnostic approaches, necropsy protocols and microbiological data from 1994 and 1995 were reviewed. Among 694 necropsies from 1693 patients who died in these two years, 27 (4%) cases of invasive aspergillosis were identified. Twelve cases of invasive aspergillosis were found after transplantation of solid organs, three after bone marrow transplantation, four in patients with haematological malignancies, and five in patients with solid tumours. In 15 cases (56%) invasive aspergillosis was not suspected before death. In patients in whom serum sampling was performed seven days antemortem, the Aspergillus latex agglutination test had a sensitivity of 53% (9/17). Culture of tracheal secretions or bronchoalveolar lavage fluid from patients with pulmonary aspergillosis yielded Aspergillus fumigatus in 88% (14/16). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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