Thallium-201 SPECT in the evaluation of early effects on brain tumors treated with stereotactic irradiation
| Autor: | Kazuo Mizoi, Noriaki Tomura, Akira Anbai, Koichi Omachi, Hiroyuki Kidani, Jiro Watarai, Satoshi Takahashi, Kazuhumi Sasaki, Junichi Izumi, Akira Suzuki, Ikuo Sakuma |
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| Rok vydání: | 2005 |
| Předmět: |
Treatment response
chemistry.chemical_element urologic and male genital diseases Radiosurgery Sensitivity and Specificity Severity of Illness Index Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Thallium Neoplasm Staging Postoperative Care Tomography Emission-Computed Single-Photon medicine.diagnostic_test Tumor size business.industry Brain Neoplasms virus diseases Reproducibility of Results Magnetic resonance imaging General Medicine Prognosis Magnetic Resonance Imaging female genital diseases and pregnancy complications Treatment Outcome chemistry Radiopharmaceuticals Nuclear medicine business Stereotactic irradiation |
| Zdroj: | Clinical nuclear medicine. 30(2) |
| ISSN: | 0363-9762 |
| Popis: | Purpose: To determine whether thallium-201 SPECT can predict response to stereotactic irradiation (STI) earlier than magnetic resonance imaging (MRI), the change in tumor size measured by MRI was compared with the change in tumor activity measured by T1-201 SPECT before and after STI. Materials and Methods: Twenty-one tumors in 16 patients with intracranial tumors were treated by STI. T1-201 SPECT was performed within 1 week before the beginning of STI and within 1 week after the end of STI in all patients. All patients underwent MRI within 1 week before the beginning of STI, and 14 patients (19 tumors) underwent MRI within 1 week after the end of STI. Follow-up MRI was performed 1 to 2 months after the end of STI in 14 patients (16 tumors). The activity of T1-201 in the tumor divided by that of the uninvolved symmetric area was defined as the Tl-index. The change in tumor size immediately and I to 2 months after STI was compared with the change in T1-index immediately after STI. Results: No significant relationship between the ratio of tumor size immediately after STI and the ratio of T1-index immediately after STI was found. A significant correlation (r = 0.69, P |
| Databáze: | OpenAIRE |
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