A False-Negative Case of Primary Central Nervous System Lymphoma on 11C-Methionine PET and Intense 18F-FDG Uptake
| Autor: | Miguel Baquero, Eduard Riera, Jose Ramon Garcia-Garzon, Pere Bassa, Diego Villasboas-Rosciolesi, Marina Soler |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Lymphoma 030218 nuclear medicine & medical imaging Central Nervous System Neoplasms Lesion 18f fdg uptake 03 medical and health sciences Methionine 0302 clinical medicine Fluorodeoxyglucose F18 Glioma medicine Humans Radiology Nuclear Medicine and imaging Carbon Radioisotopes False Negative Reactions Pathological 11c methionine pet business.industry Primary central nervous system lymphoma General Medicine medicine.disease Magnetic Resonance Imaging Negative case Positron-Emission Tomography 030220 oncology & carcinogenesis Radiopharmaceuticals medicine.symptom business |
| Zdroj: | Clinical Nuclear Medicine. 41:664-665 |
| ISSN: | 0363-9762 |
| Popis: | We report a case of a 44-year-old man with neurological symptoms and MRI findings, which were unable to differentiate between glioma and lymphoma. Metabolic characterization by means of PET imaging with F-FDG and C-methionine is proposed to determine the benign or tumor (high- and low-grade) origin of brain lesions. In this case, the MRI lesion corresponded with an inconclusive metabolic pattern of intense F-FDG uptake and no significant C-methionine uptake. Pathological study revealed a false-negative case of C-methionine due to lymphoma. |
| Databáze: | OpenAIRE |
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