Antigenic and genetic analyses of isolate APMV/wigeon/Italy/3920-1/2005 indicate that it represents a new avian paramyxovirus (APMV-12)
| Autor: | Alireza Heidari, Isabella Monne, D. J. Alexander, Maria Serena Beato, Ilaria Capua, Calogero Terregino, Ruth J. Manvell, Wendy M. Shell, E. W. Aldous, Chad M. Fuller, Ian H. Brown, R. De Nardi |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Sequence analysis
Genome Viral medicine.disease_cause Genome Phylogenetics Virology medicine Animals Avulavirus Phylogeny Poultry Diseases biology Phylogenetic tree Bird Diseases Avulavirus Infections Nucleic acid sequence Sequence Analysis DNA General Medicine Hemagglutination Inhibition Tests Wigeon biology.organism_classification Influenza A virus subtype H5N1 Ducks Italy RNA Viral Immunization Chickens |
| Popis: | Isolate wigeon/Italy/3920-1/2005 (3920-1) was obtained during surveillance of wild birds in November 2005 in the Rovigo province of Northern Italy and shown to be a paramyxovirus. Analysis of cross-haemagglutination-inhibition tests between 3920-1 and representative avian paramyxoviruses showed only a low-level relationship to APMV-1. Phylogenetic analysis of the whole genome and each of the six genes indicated that while 3920-1 grouped with APMV-1 and APMV-9 viruses, it was quite distinct from these two. In the whole-genome analysis, 3920-1 had 52.1 % nucleotide sequence identity to the closest APMV-1 virus, 50.1 % identity to the APMV-9 genome, and less than 42 % identity to representatives of the other avian paramyxovirus groups. We propose isolate wigeon/Italy/3920-1/2005 as the prototype strain of a further APMV group, APMV-12. |
| Databáze: | OpenAIRE |
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