The appearance of 20α-hydroxysteroid dehydrogenase activity in preovulatory follicles of immature rats treated with pregnant mare serum gonadotropin
| Autor: | M. Raanan, A. Nimrod, S. Cohen, Benjamin Eckstein, N. Lerner |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Ovulation
endocrine system medicine.medical_specialty Gonadotropins Equine Dehydrogenase Pregnant Mare Serum Gonadotropin Biochemistry Endocrinology Ovarian Follicle Pregnancy Internal medicine Follicular phase medicine Animals Hydroxysteroid dehydrogenase Incubation reproductive and urinary physiology chemistry.chemical_classification urogenital system Hydroxysteroid Dehydrogenases Rats Kinetics Enzyme chemistry Female Proestrus hormones hormone substitutes and hormone antagonists |
| Zdroj: | Journal of Steroid Biochemistry. 8:213-216 |
| ISSN: | 0022-4731 |
| DOI: | 10.1016/0022-4731(77)90053-x |
| Popis: | 20α-Hydroxysteroid dehydrogenase (20α-SDH) activity, believed to be present exclusively in regressing corpora lutea, was demonstrated in preovulatory follicles of immature rats exposed 52 h previously to pregnant mare serum gonadotropin (PMSG). Production of progesterone from 20α-dihydroprogesterone was proportional to enzyme concentration and time of incubation, and obeyed Michaelis-Menten kinetics. Induction of follicular 20α-SDH activity is not dependent on the LH surge, since the same activity was found in follicles before and after exposure to the first LH surge. |
| Databáze: | OpenAIRE |
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