Titanium tetrachloride immobilized on cross-linked poly(N-vinyl-2-pyrrolidone) as a recyclable heterogeneous catalyst for one-pot three component synthesis of 3, 4-dihydropyrimidin-2(1H)-ones/thiones

Autor:	Ali Rahmatpour, Ghazaleh Donyapeyma
Rok vydání:	2022
Předmět:	Organic Chemistry
Zdroj:	Synthetic Communications. 52:678-693
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397911.2022.2045322
Popis:	A new catalytic application of titanium tetrachloride immobilized on the cross-linked poly(N-vinyl-2-pyrrolidone) carrier as beads, TiCl4/PNVP, as a recoverable and heterogeneous macromolecular Lewis acidic catalyst is developed. This catalytic system allowed for the facile and cleaner synthesis of 3,4-dihydro pyrimidin-2(1H)-ones/thiones in high yields with TON up to 23.2 through the Biginelli three-component cyclocondensation reaction in ethanol. The reusability test ascertained that this heterogeneous titanium catalyst can be easily separated from the reaction mixture by simple filtration and reused several times with no great decline of activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eea13834212f6b0dfbefa682c3b2140 https://doi.org/10.1080/00397911.2022.2045322 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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