Dynamics of venom composition across a complex life cycle
| Autor: | Vengamanaidu Modepalli, Yaara Y Columbus-Shenkar, Arie Fridrich, Maria Y. Sachkova, Yehu Moran, Kartik Sunagar |
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| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
0303 health sciences Larva food.ingredient biology Zoology Nematostella Embryo Venom Sea anemone biology.organism_classification complex mixtures 010603 evolutionary biology 01 natural sciences Transgenesis Transcriptome 03 medical and health sciences food 14. Life underwater Planula 030304 developmental biology |
| DOI: | 10.1101/159889 |
| Popis: | Little is known about venom in young developmental stages of animals. The appearance of stinging cells in very early life stages of the sea anemone Nematostella vectensis suggests that toxins and venom are synthesized already in eggs, embryos and larvae of this species. Here we harness transcriptomic and biochemical tools as well as transgenesis to study venom production dynamics in Nematostella. We find that the venom composition and arsenal of toxin-producing cells change dramatically between developmental stages of this species. These findings might be explained by the vastly different ecology of the larva and adult polyp as sea anemones develop from a miniature non-feeding mobile planula to a much larger sessile polyp that predates on other animals. Further, the results suggest a much wider and dynamic venom landscape than initially appreciated in animals with a complex life cycle. |
| Databáze: | OpenAIRE |
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