Effect of clinical factors on trajectory of functional performance in patients undergoing hemodialysis

Autor:	Wen-Chin Lee, Sin-Hua Moi, Jin-Bor Chen, Lung-Chih Li, Cheng-Hong Yang
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty Karnofsky Scale medicine.medical_treatment Taiwan 030232 urology & nephrology 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine karnofsky scale 03 medical and health sciences 0302 clinical medicine Renal Dialysis Risk Factors Internal medicine medicine Humans In patient Longitudinal Studies Karnofsky Performance Status skin and connective tissue diseases albumin Aged Retrospective Studies hemodialysis business.industry General Medicine Middle Aged humanities Diseases of the genitourinary system. Urology body regions Logistic Models age Nephrology Multivariate Analysis Clinical Study Kidney Failure Chronic Female sense organs Hemodialysis RC870-923 business Research Article
Zdroj:	Renal Failure, Vol 43, Iss 1, Pp 90-96 (2021) Renal Failure article-version (VoR) Version of Record
ISSN:	1525-6049
Popis:	Purpose This study aimed to investigate the association between clinical factors and temporary changes in functional performance in patients undergoing hemodialysis. Methods This was a retrospective, longitudinal observational study conducted from 2015 to 2017. Eight-two patients undergoing hemodialysis in the outpatient clinic were enrolled. Functional performance was measured using the Karnofsky Performance Status (KPS) scale. Collected data for analysis included demographics, laboratory parameters, and KPS scale scores. All participants were grouped into a high KPS cluster and a low KPS cluster based on dynamic changes in KPS scales from 2015 to 2017. Results Participants in the high KPS cluster demonstrated an approximate trend, and those in the low KPS cluster demonstrated a low pattern. By stepwise selection model analysis, age (OR 1.12, 95% CI 1.03–1.23, p = 0.011), serum BUN (OR 1.08, 95% CI 1.02–1.16, p = 0.015), calcium levels (OR 3.24, 95% CI 1.2–8.73, p = 0.02), and beta-2-microglobulin (OR > 1.0, CI >1.00
Databáze:	OpenAIRE
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