Roux-en-Y choledochojejunostomy using novel magnetic compressive anastomats in canine model of obstructive jaundice
Autor: | Zheng Wu, Jianhui Li, Liang Yu, Shiqi Liu, Xiaopeng Yan, Yi Lv, Chao Fan, Chun-Bao Wang |
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Rok vydání: | 2012 |
Předmět: |
Male
medicine.medical_specialty Time Factors Anastomosis Choledochostomy Surgical Equipment Stoma Magnetics Dogs Animals Medicine Hepatology Common bile duct business.industry Gastroenterology Anastomosis Roux-en-Y Bilirubin Equipment Design Jaundice medicine.disease Surgery Disease Models Animal Jaundice Obstructive Apposition Stenosis medicine.anatomical_structure Obstructive jaundice medicine.symptom business Biomarkers |
Zdroj: | Hepatobiliary & Pancreatic Diseases International. 11:81-88 |
ISSN: | 1499-3872 |
DOI: | 10.1016/s1499-3872(11)60129-x |
Popis: | Background The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications has remained high. A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients. Methods After ligating the common bile duct for 7 days, 16 dogs were randomly divided into two groups ( n =8 per group). Anastomats were used in the study group, and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy. We compared the operation time, incidence of complications, gross appearance, and pathological disparity in stoma between the two groups in 1-month and 3-month follow-up examinations. Results The time spent on constructing the anastomosis for the study group was significantly shortened. Although no anastomotic stenosis occurred in the two groups, the narrowing rate of biliary-enteric anastomosis was much higher in the control group. There was one case of bile leakage in the control group, whereas no bile leakage occurred in the study group. A smoother surface, an improved layer apposition, and a lower local inflammatory response were identified in the anastomosis of the study group. Conclusion The structures of the novel magnetic compressive anastomats are simple, and they are time-saving, safe and efficient for performing Roux-en-Y choledochojejunostomy procedures in a canine model of obstructive jaundice. |
Databáze: | OpenAIRE |
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