Hemophagocytic Syndrome as Uncommon Cause of Severe Pancytopenia After Liver Transplantation
| Autor: | Esteban Fuentes Valenzuela, Laura Sánchez Delgado, Gloria Sánchez-Antolín, Rodrigo Nájera Muñoz, Carolina Almohalla Álvarez, Elena Fernández-Fontecha, Félix García-Pajares, Javier Tejedor Tejada, Carmen Alonso Martín, Carlos Maroto Martín, Ana Campano García |
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| Rok vydání: | 2020 |
| Předmět: |
Epstein-Barr Virus Infections
Herpesvirus 4 Human medicine.medical_specialty Pancytopenia medicine.medical_treatment Liver transplantation Gastroenterology Lymphohistiocytosis Hemophagocytic Virus Fatal Outcome Postoperative Complications hemic and lymphatic diseases Internal medicine medicine Humans Initial treatment In patient Transplantation business.industry High mortality Middle Aged medicine.disease Liver Transplantation medicine.anatomical_structure Female Surgery Bone marrow business |
| Zdroj: | Transplantation Proceedings. 52:1500-1502 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2020.02.060 |
| Popis: | Background A rare but life-threatening cause of pancytopenia after liver transplantation is hemophagocytic syndrome. We present a 48-year-old woman who underwent liver transplantation and developed a hemophagocytic syndrome secondary to Epstein-Barr virus with a fatal course, despite initial treatment with immunosuppressants. The diagnosis was made based on the bone marrow aspiration, in which macrophages with phagocytic activity were observed, and clinical findings. Due to the very poor outcomes and high mortality, in patients with severe pancytopenia hemophagocytic syndrome should be excluded, and a bone marrow aspiration should be considered. |
| Databáze: | OpenAIRE |
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