Total intravenous anesthesia with propofol is associated with a lower rate of postoperative delirium in comparison with sevoflurane anesthesia in elderly patients
| Autor: | Koji Sumikawa, Katsumi Hara, Shoji Matsunaga, Kouko Toba, Tetsuya Hara, Hikoma Yamashita, Daiji Akiyama, Tetsuji Makita, Koji Ishii |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Methyl Ethers medicine.medical_specialty Sevoflurane 03 medical and health sciences symbols.namesake 0302 clinical medicine Postoperative Complications Double-Blind Method Medicine Humans Postoperative delirium 030212 general & internal medicine Prospective Studies Prospective cohort study Propofol Fisher's exact test Aged Aged 80 and over business.industry Incidence (epidemiology) Incidence Delirium Surgery Anesthesiology and Pain Medicine Anesthesia Anesthesia Recovery Period Anesthetics Inhalation symbols Anesthesia Intravenous Female business Complication 030217 neurology & neurosurgery Anesthetics Intravenous medicine.drug Sevoflurane anesthesia |
| Zdroj: | Journal of clinical anesthesia. 33 |
| ISSN: | 1873-4529 |
| Popis: | Study objective Postoperative delirium (POD) is a common complication of anesthesia. The incidence of POD in elderly patients ranges from 37% to 53%, and POD increases the morbidity and mortality of elderly patients. However, the effects of anesthetics on POD are not well known. The present study aimed to compare the incidence of POD resulting from propofol and sevoflurane anesthesia. Design Double-blind prospective study. Setting Operating room and postoperative recovery area. Patients Thirty patients in the sevoflurane anesthesia group and 29 in the propofol anesthesia group. Measurements Statistical analyses were performed using Microsoft Excel 2010 for Windows 7 (Microsoft Corporation, Redmond, Wash). Statistical analysis was performed using Fisher exact test and Student t test. Main Results The incidence of POD in the propofol anesthesia (6.9%) was significantly less than that observed in the sevoflurane anesthesia (26.7%; 038). Conclusion In comparison with sevoflurane anesthesia, propofol anesthesia is associated with a lower incidence of POD in elderly patients. |
| Databáze: | OpenAIRE |
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